Sports Nutrition Online Event

October 22, 2015

3:30 PM CET (9:30 AM ET)

Market Segment: Dietary Supplement

As consumers increasingly focus on living a healthy life, the appeal of sports nutrition products is broadening from bodybuilders and professional athletes to also include everyday active adults.

In his virtual presentation at the Sports Nutrition Online Event, Dominik Mattern, Business Development Manager, EMEA, will discuss the important role that dosage form selection plays in driving consumer preference for sports nutrition products.

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Sports Nutrition Online Event

October 22, 2015

3:30 PM CET (9:30 AM ET)

Market Segment: Dietary Supplement

Click here for access

Hot-Melt Extrusion Fundamentals: Processing of Amorphous Solid Dispersions for Poorly Soluble Drugs

October 06, 2015

8:00 AM PT (5:00 PM CET)

Market Segment: Pharmaceutical

In this webinar, scientists from Bend Research will provide insight into HME fundamentals, including solid dispersion formulation selection. Strategies and case studies for solid dispersion formulation selection and definition of a HME process operating space will be reviewed.

An estimated 60 percent of compounds in early development have poor solubility due to low solubility and dissolution rates (DCS IIa and IIb). Hot-melt extrusion (HME) of amorphous solid dispersions is one approach Bend Research, a division of Capsugel Dosage Form Solutions, uses to address APIs with limited bioavailability. By using small scale screening techniques and an integrated process and formulation approach, Bend Research is able to rapidly develop a progressable drug intermediate and dosage form for preclinical and clinical manufacture. These approaches balance the target absorption profile, manufacturability, physical and chemical stability, and API availability.

Presented By:

• Charlie McLaughlin, Engineering Technical Group Lead
• Scott Bone, Chemistry Technical Group Lead

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Hot-Melt Extrusion Fundamentals: Processing of Amorphous Solid Dispersions for Poorly Soluble Drugs

October 06, 2015

8:00 AM PT (5:00 PM CET)

Market Segment: Pharmaceutical

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Product Development Using the NDA 505(b)(2) Pathway

September 29, 2015

8:00 AM PT (11:00 AM ET)

Market Segment: Pharmaceutical

The 505(b)(2) NDA pathway is increasingly utilized to bring improved and differentiated products to market faster and more cost effectively. 

505(b)(2)  products often utilize enabling technologies to create better medicines through new formulations, new dosage forms, and new combinations which can result in up to 7 years of market exclusivity dependent. Join Camargo and Capsugel in discussing 505(b)(2) challenges, recent regulatory updates, and case studies demonstrating successful application of enabling technologies in 505(b)(2) product development. 

Presented by:

• Ken Phelps, President & CEO, Camargo Pharmaceutical Services

• Trevor Wigle, Director of Product Development, Capsugel Dosage Form Solutions

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Product Development Using the NDA 505(b)(2) Pathway

September 29, 2015

8:00 AM PT (11:00 AM ET)

Market Segment: Pharmaceutical

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Fundamentals of Spray-Dried Dispersion Technology

September 17, 2015

3:00 PM CET (9:00 AM EDT)

Market Segment:

In this webinar, experts will discuss:

• Key parameters that indicate amorphous dispersions and specifically spray dry dispersions as an optimal enabling approach.
• How the spray drying process can be scaled from tens of milligrams to metric tons.
• Best practices for formulation screening and evaluation of stability, performance, and manufacturability of spray-dried dispersions.
• Methodologies and tools for spray drying process development and scale-up through clinical supply and commercial manufacturing.

Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment, which often translates to rapid absorption and improved bioavailability. Amorphous solid dispersions are typically prepared by using hot-melt extrusion or spray drying processes. This webinar will focus on the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.

Presented By:

• Amber Broadbent, Ph.D., Director of Engineering
• Nathan Bennette, Senior Research Chemist

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Fundamentals of Spray-Dried Dispersion Technology

September 17, 2015

3:00 PM CET (9:00 AM EDT)

Market Segment:

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Sports Nutrition to Active Nutrition: What is fueling the transformation?

July 29, 2015

2 PM ET (8 PM CET)

Market Segment: Dietary Supplement

Sports nutrition is no longer just for the traditional athlete or gym enthusiast. A transformation is underway as manufacturers contemplate moving sports nutrition into the mass market to meet consumer’s need for products that increase stamina, sustain energy, enhance recovery and are science-backed with clean ingredients. These products need to fit into their healthy lifestyle and should not be complicated or have special regimens. 

Companies need to understand how to successfully make this transition. By understanding emerging segments and leveraging the right ingredients they may make a better transition to the mass market shelves. The ways these ingredients need to be delivered will impact that success.

Speakers:

• Douglas S. Kalman PhD, RD, FACN, Dir, DB Nutrition & Endocrinology, QPS MRA
• Jeff Hilton, Partner and Co-Founder, BrandHive
• Missy Lowery, Sr. Marketing Manager, Capsugel

Outline:

• Recognize the emerging consumer segments fueling the transformation
• Learn about key ingredients moving from the gym to mainstream
• Leverage delivery systems to optimize key ingredient performance and consumer appeal

Register here

Sports Nutrition to Active Nutrition: What is fueling the transformation?

July 29, 2015

2 PM ET (8 PM CET)

Market Segment: Dietary Supplement

Click here for access