Next Generation HPMC Capsules: Bioequivalence and Functional Performance

February 17, 2016 2016-02-17 10:00:00 2016-02-17 11:00:00 America/New_York Next Generation HPMC Capsules: Bioequivalence and Functional Performance Join our upcoming webinar that will present new in-vivo data demonstrating the performance characteristics of the next generation of HPMC capsules. Register here for this webinar! 4 PM CET (10 AM ET)

4 PM CET (10 AM ET)

Market Segment: Pharmaceutical

Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug delivery when there is a physical incompatibility with gelatin. A new HPMC-polymer capsule without secondary gelling agents developed through a thermo-gelation process (Vcaps® Plus) has shown dissolution profiles similar to hard gelatin capsules, including pH and ionic independence.

Although HPMC capsules are used in marketed drugs, there are few comparisons of the in vivo performance between gelatin and HPMC in literature. In this webinar, experts will present the in vitro dissolution and an in vivo bioequivalence study comparing the performance of the identical formulation of three different drugs in Vcaps Plus capsules to Hard Gelatin Capsules (HGC). In addition, the circumstances under which the same API and formulation contained in HGC and Vcaps Plus can be expected to provide equivalent performance will be discussed. 

Presented by:

• Matt Richardson, PhD, Manager, Pharmaceutical Business Development, Capsugel
• Michael Morgen, PhD, Senior Principal Scientist, Bend Research

Register here

Next Generation HPMC Capsules: Bioequivalence and Functional Performance

January 19, 2016 2016-01-19 11:00:00 2016-01-19 12:00:00 America/New_York Next Generation HPMC Capsules: Bioequivalence and Functional Performance Join our upcoming webinar that will present new in-vivo data demonstrating the performance characteristics of the next generation of HPMC capsules. Register here for this webinar! 11 AM ET (5 PM CET)

11 AM ET (5 PM CET)

Market Segment: Pharmaceutical

Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug delivery when there is a physical incompatibility with gelatin. A new HPMC-polymer capsule without secondary gelling agents developed through a thermo-gelation process (Vcaps® Plus) has shown dissolution profiles similar to hard gelatin capsules, including pH and ionic independence.

Although HPMC capsules are used in marketed drugs, there are few comparisons of the in vivo performance between gelatin and HPMC in literature. In this webinar, experts will present the in vitro dissolution and an in vivo bioequivalence study comparing the performance of the identical formulation of three different drugs in Vcaps Plus capsules to Hard Gelatin Capsules (HGC). In addition, the circumstances under which the same API and formulation contained in HGC and Vcaps Plus can be expected to provide equivalent performance will be discussed. 

Presented by:

• Matt Richardson, PhD, Manager, Pharmaceutical Business Development, Capsugel
• Michael Morgen, PhD, Senior Principal Scientist, Bend Research

Register here

Performance of gelatin capsules and the next generation of HPMC capsules - Vcaps® Plus

December 10, 2015 2015-12-10 15:42:00 2015-12-10 15:42:00 America/New_York Performance of gelatin capsules and the next generation of HPMC capsules - Vcaps® Plus Though HPMC capsules are used in marketed drugs, there are few comparisons on the in-vivo performance between gelatin and HPMC available in literature. Learn more during this webinar! 1 PM ET (7 PM CET - 10 AM PT)

1 PM ET (7 PM CET - 10 AM PT)

Market Segment: Pharmaceutical

Though HPMC capsules are used in marketed drugs, there are few comparisons of the in vivo performance between gelatin and HPMC available in literature. In this webinar, we present the results of in vitro dissolution and an in vivo bioequivalence study comparing the performance of the identical formulation of three different drugs in Vcaps® Plus capsules to HGC. In addition, the circumstances under which the same API and formulation contained in HG and Vcaps® Plus can be expected to provide equivalent performance will be discussed.

In this webinar, you will learn:

• Characteristics of the next generation of HPMC capsules
• The in vitro and in vivo performance comparison of HGC vs. HPMC for several drugs
• Mechanistic situations that can influence relative performance of HCG vs. HPMC for specific delivery applications

​Presented by:

• Matt Richardson, Ph.D., Manager, Pharmaceutical Business Development, Capsugel
• Michael Morgen, Ph.D., Senior Principal Scientist, Capsugel Dosage Form Solutions

Register here

The Top 4 Most Expensive Encapsulation Mistakes and How to Avoid Them

December 03, 2015 2015-12-03 11:46:00 2015-12-03 11:46:00 America/New_York The Top 4 Most Expensive Encapsulation Mistakes and How to Avoid Them Encapsulation manufacturing has grown as companies seek faster ways to develop and complete products for commercialization. Learn more about four key areas manufacturing and R&D must address! 1 PM ET (7 PM CET)

1 PM ET (7 PM CET)

Market Segment: Pharmaceutical

Encapsulation manufacturing has grown as companies seek faster ways to develop and complete products for commercialization. This webinar will examine four key areas manufacturing and R&D must address to ensure they don’t fall victim to encapsulation mistakes.

What you'll learn:

• About the formulation in the Quality by Design space
• How equipment maintenance affects encapsulation
• How proper training can help prevent costly mistakes
• How standardization ensures quality

These simple basics are often simply overlooked with significant and costly results. Black-belt quality and engineering specialists will provide the pathway forward to ensure those mistakes can be avoided.

Presented by:

• John Davidson, Senior Manager Quality Engineering Services, Capsugel
• Jose Maldonado, Senior Engineer Field Services, Capsugel
• Paul Davis, Technical Service Engineer, Capsugel

Register here

Pre & Probiotics Online Event

November 17, 2015 2015-11-17 11:54:00 2015-11-17 11:54:00 America/New_York Pre & Probiotics Online Event During the Pre & Probiotics Online Event, Nicolas Madit, Business Development Manager EMEA, will review Capsugel's portfolio of innovative solutions to support the growing probiotic market. 10:45 AM CET

10:45 AM CET

Market Segment: Dietary Supplement

In this webinar at the Pre & Probiotics Online Event, Nicolas Madit, Business Development Manager EMEA, will review Capsugel's portfolio of innovative solutions to support the growing probiotic market. He will address existing concerns about lengthening shelf life with low moisture capsules, increasing probiotic release in the intestine with DRcaps™ and propose alternatives for delivering probiotic to pediatric and / or patients with swallowing difficulties.

Register here